Andouard mentions an instance of blue bile in a woman, blue flakes being found in her vomit. There was no trace of copper to be found in this case. Andouard says that the older physicians frequently spoke of this occurrence.
Rhodius speaks of the sweat being sweet after eating honey; the Ephemerides and Paullini also mention it. Chromidrosis, or colored sweat, is an interesting anomaly exemplified in numerous reports. Black sweat has been mentioned by Bartholinus, who remarked that the secretion resembled ink; in other cases Galeazzi and Zacutus Lusitanus said the perspiration resembled sooty water. Phosphorescent sweat has been recorded. Paullini and the Ephemerides mention perspiration which was of a leek-green color, and Borellus has observed deep green perspiration. Marcard mentions green perspiration of the feet, possibly due to stains from colored foot-gear. The Ephemerides and Paullini speak of violet perspiration, and Bartholinus has described perspiration which in taste resembled wine.
Sir Benjamin Brodie has communicated the history of a case of a young girl of fifteen on whose face was a black secretion. On attempting to remove it by washing, much pain was caused. The quantity removed by soap and water at one time was sufficient to make four basins of water as black as if with India ink. It seemed to be physiologically analogous to melanosis. The cessation of the secretion on the forehead was followed by the ejection of a similar substance from the bowel, stomach, and kidney. The secretion was more abundant during the night, and at one time in its course an erysipelas-eruption made its appearance. A complete cure ultimately followed.
Purdon describes an Irish married woman of forty, the subject of rheumatic fever, who occasionally had a blue serous discharge or perspiration that literally flowed from her legs and body, and accompanied by a miliary eruption. It was on the posterior portions, and twelve hours previous was usually preceded by a moldy smell and a prickly sensation. On the abdomen and the back of the neck there was a yellowish secretion. In place of catamenia there was a discharge reddish-green in color. The patient denied having taken any coloring matter or chemicals to influence the color of her perspiration, and no remedy relieved her cardiac or rheumatic symptoms.
The first English case of chromidrosis, or colored sweat, was published by Yonge of Plymouth in 1709. In this affection the colored sweating appears symmetrically in various parts of the body, the parts commonly affected being the cheeks, forehead, side of the nose, whole face, chest, abdomen, backs of the hands, finger-tips, and the flexors, flexures at the axillae, groins, and popliteal spaces. Although the color is generally black, nearly every color has been recorded. Colcott Fox reported a genuine case, and Crocker speaks of a case at Shadwell in a woman of forty-seven of naturally dark complexion. The bowels were habitually sluggish, going three or four days at least without action, and latterly the woman had suffered from articular pains.
The discolored sweat came out gradually, beginning at the sides of the face, then spreading to the cheeks and forehead. When seen, the upper half of the forehead, the temporal regions, and the skin between the ear and malar eminence were of a blackish-brown color, with slight hyperemia of the adjacent parts; the woman said the color had been almost black, but she had cleaned her face some. There was evidently much fat in the secretion; there was also seborrhea of the scalp. Washing with soap and water had very little effect upon it; but it was removed with ether, the skin still looking darker and redder than normal.
After a week's treatment with saline purgatives the discoloration was much less, but the patient still had articular pains, for which alkalies were prescribed; she did not again attend. Crocker also quotes the case of a girl of twenty, originally under Mackay of Brighton. Her affection had lasted a year and was limited to the left cheek and eyebrow. Six months before the patch appeared she had a superficial burn which did not leave a distinct scar, but the surface was slightly granular. The deposit was distinctly fatty, evidently seborrheic and of a sepia-tint. The girl suffered from obstinate constipation, the bowels acting only once a week. The left side flushed more than the right In connection with this case may be mentioned one by White of Harvard, a case of unilateral yellow chromidrosis in a man. Demons gives the history of a case of yellow sweat in a patient with three intestinal calculi.
Wilson says that cases of green, yellow, and blue perspiration have been seen, and Hebra, Rayer, and Fuchs mention instances.
Conradi records a case of blue perspiration on one-half the scrotum. Chojnowski records a case in which the perspiration resembled milk.